The article notes that the processes in the human body are passing. Among them are rapid growth in childhood, a plateau of early adulthood and accelerated aging at the age of about 50 years.
According to a study of proteins in the human body, it is after the achievement of this age that the trajectory of aging tissues and organs becomes more steep than in the previous decades. The blood vessels wear out especially quickly.
Researchers studied how proteins in various tissues change over time. They collected tissue samples in 76 organs aged 14 to 68 years old, who died from random traumatic brain injury.
The samples covered seven body systems: cardiovascular (heart and aorta), digestive (liver, pancreas and intestines), immune (spleen and lymph nodes), endocrine (adrenal glands and white adipose tissue), respiratory (lungs), cover (leather) and supporting (muscles). Samples of blood were also taken.
The team compiled a catalog of proteins found in these systems, carefully monitoring the change in their level with the age of donors. Researchers compared their results with the database of these diseases and related genes and found that the expression of 48 proteins associated with diseases increases with age. These include cardiovascular diseases, tissue fibrosis, fatty liver and liver tumor. The most pronounced changes occur aged 45 to 55 years.
Previous studies of other researchers have revealed two more peaks of aging: about 44 years and about 60 years. The new result indicates that human aging is a complex, phased process affecting various systems, is noted in publication.
